Change of absolute neutrophil count after intravenous immunoglobulin administration for the children with idiopathic thrombocytopenic purpura

نویسندگان

  • Heung Sik Kim
  • Hyun Jung Shin
  • Byung Kyu Choe
  • Jun Sik Kim
چکیده

접수 : 2007년 5월 19일, 승인 : 2007년 7월 17일 책임저자 :김흥식, 계명의대 동산의료원 소아과 Correspondence : Heung Sik Kim, M.D. Tel : 053)250-7516 Fax : 053)250-7783 E-mail : [email protected] 대한 자가 항체가 생겨 혈소판에 부착한 후 비장과 같은 망상내피 세포계에서 파괴됨으로써 혈소판 감소증이 나타나는 것으로 생각 되고 있다 2) . 혈소판감소증의 정도와 출혈 정도에 따라 저절로 호전되는 것 을 기대하며 관찰만 하는 경우도 있지만, 두개내 출혈과 같은 심 각한 출혈을 예방하기 위하여 적극적인 치료를 하기도 한다 3) . 치 료 약제로는 면역 글로불린, 항-D 항체, 스테로이드 등이 사용되 며 그 중 어린 소아에서는 면역 글로불린이 초기 치료로 사용되는 경우가 많다 4) . 면역 글로불린의 사용에 있어 다양한 부작용이 보 고된 바는 있으나 그 빈도는 낮은 편이며 심각한 부작용은 드물다 특발성혈소판감소성자반증 환아에서 정주용 면역 글로불린 투여 후 절대 호중구 수치의 변화

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تاریخ انتشار 2007